Spero Therapeutics, Inc.
Spero Therapeutics, Inc is a Healthcare company operating in Biotechnology with a $128.0M market cap.
Most recent earnings call: Q2 FY25 on Aug 12, 2025.
15 earnings calls indexed on Spoken Alpha.
Behavioral analysis
Disclosures
Extracted from Unknown source, 2026-06-21.
Transcripts
Most recent calls indexed for this ticker. Open any call to drill into prepared remarks and Q&A.
History
Reported quarters with consensus, surprise, and 1-day reaction context.
Spoken Alpha tracks SPRO's historical accountability: how often management beat consensus, how the stock reacted, and how guidance evolved across the cycle. The figures below are illustrative placeholder data generated for layout — they will be replaced with real deviation metrics, True Consensus values, and EODHD price reactions as those data layers land.
Misses consensus 10/10 quarters
SampleSpoken Alpha builds an accountability record per executive — how the person's own guidance, language, and reactions have evolved across every call they've appeared on. The one-liners below are illustrative placeholder data pending the deviation v1 work. Click any name for the full role timeline and call appearance history.
Peers
Sector peers tracked by Spoken Alpha. Each links to the same machine-readable IR surface — earnings calls, executives, and accountability scores.
API
The same data on this page is available as a machine-readable feed via the Spoken Alpha API. One call returns the IR URL, recent transcripts, and accountability scores for SPRO.
$ curl https://api.spokenalpha.com/v1/companies/SPROFAQ
Spoken Alpha indexes SPRO's earnings call transcripts at https://spokenalpha.com/companies/SPRO. Each call links to attributed speakers and parsed analyst Q&A. Spero Therapeutics, Inc.'s own investor relations page is at https://www.sperotherapeutics.com/investor-relations.
Spero Therapeutics, Inc. (SPRO) held its most recent earnings call on 2025-08-12, covering fiscal Q2 2025.
Spero Therapeutics, Inc. (SPRO) operates in the Healthcare sector (Biotechnology industry).
Repeated misses without a guidance reset suggest management is structurally optimistic relative to operating reality. Track whether next-quarter guidance is being benchmarked off the prior miss or the prior plan.
Missed in 4 of the last 4 quarters
SampleRecent misses matter more than long-window beat rate — the trailing 12 months drives the analyst model and the next-print bar.
| Quarter | Actual EPS | Consensus | Surprise | 1D | 5D |
|---|---|---|---|---|---|
| Q1 FY2025 | $1.49 | $1.70 | -12.3% | -3.6% | -6.5% |
| Q4 FY2025 | $1.41 | $1.58 | -10.5% | +5.3% | +7.9% |
| Q3 FY2025 | $1.63 | $1.77 | -7.7% | +5.8% | +6.0% |
| Q2 FY2025 | $1.77 | $1.78 | -0.7% | +5.0% | +7.5% |
| Q1 FY2024 | $1.57 | $1.59 | -1.5% | -0.8% | +2.1% |
OTHER since 2024 • 2/4 beats (50%) • guidance suspended Q1 FY2025
CEO since 2024 • 3/4 beats (75%) • last guidance cut Q2 FY2025
| Q4 FY2024 |
| $1.39 |
| $1.61 |
| -13.5% |
| +1.5% |
| +2.6% |
| Q3 FY2024 | $1.50 | $1.69 | -11.4% | +0.7% | -0.4% |
| Q2 FY2024 | $1.41 | $1.68 | -16.2% | +4.7% | +2.3% |
| Q1 FY2023 | $1.49 | $1.69 | -12.1% | +2.9% | +2.2% |
| Q4 FY2023 | $1.90 | $1.92 | -1.0% | +0.3% | -1.5% |